22/05/2015 · What is Tay-Sachs disease

Tay-Sach is caused by a defected gene on chroBernard Sachs and Warren Tay, 19th century neurological physicians, described the progress of this disease and gave differential diagnostic criteria to tell the differences between this disease and other neurological disorders with similar symptoms....

Risk factor.Tay-Sachs Disease is considered extremely rare among the general population.

Statistically, 25% of their children will be normal (TT), 50% of their children will be carriers (Tt), and 25%of their children will be born with Tay-Sachs (tt). This principle works with most recessive diseases.


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Miguel Sena-Esteves from the Esteves Lab (Horae Gene Therapy Center) is conducting research and developing therapeutic strategies for rare inherited diseases such as the Tay-Sachs disease" width="159" height="159">Assistant Professor, Department of Neurology and Horae Gene Therapy Center


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A rarer form of the disease known as Late-Onset Tay-Sachs exists, but this paper will focus on classic infantile TSD and explore its scientific and social implications.

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Social and sociological implications.It is important to analyze the effects of Tay-Sachs Disease from a broader cultural perspective.